By Silvio Garattini
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Additional resources for Advances in Pharmacology and Chemotherapy Volume 13
Trop. Sao Paulo 8, 227-234. Camargo, M. , Correa, N. , and Peres, B. A. (1971). Rev. Inst. Med. Trop. Sao Paul0 13, 45-50. Cansado, J. R. (1973). Personal communication. Cansado, J. , Marra, U. , Faria, C. A. , Alvares, J. , and Salgado, A. A. (1969). Bol. Chil. Parasitol. 24, 2%32. , and Fernandes, J. F. (1965). Rev. Inst. Med. Trop. Sao Paulo 7, 275-282. Cerisola, J. , and Di Rissio, A. M. (1970). Rev. Inst. Med. Trop. Sao Paulo 12,403-411. Cerisola, J. , and Rabinovich, L. B. (1972). “Tratamiento de la Enfermedad de Chagas,” 75 pp.
Horizonte, Brasil. Schellenberg, K. , and Coatney, G. R. (1961). Biochem. Pharmacol. 6, 143-152. , and Taucher, E. (1968). Bol. Chil. Parasitol. 23, 149-154. , Rojas, A , , and Alfaro, E. (1969). Bol. Chil. Parusitol. 24, 66-69. , and Rojo, M. (1972). Bol. Chil. Parusitol. 27, 11-14. , and Ides, D. (1953). Antibiot. Chemother. ) 3, 117-121. , Kane, J. , and Rockenbach, J. (1952). Antibiot. Chemother. ) 2,435-437. Shoemaker, J. , and Hoffman, R. V. (1969). J. Parasitol. 5 5 , 6 5 4 4 5 9 . Shoemaker, J.
Bisquinaldine (7602 Ac) This compound, markedly active against in vivo established infections, was tested in infected HeLa cells, and found to be inactive against intra- and extracellular forms (Mieth and Seidenhat, 1967). The possibility of metabolic transformation of the drug in the living vertebrate host has not been investigated. 5. Spirotrypan An arsenical compound that has only limited value in the treatment of T . cruzi infections in vivo, spirotrypan showed activity only against extracellular forms and was unable to hinder the development of intracellular stages in infected HeLa cells (Mieth and Seidenhat, 1967).
Advances in Pharmacology and Chemotherapy Volume 13 by Silvio Garattini